Public Health Clinic |
- Keys to predict and prevent childhood atopic dermatitis
- Know your risk of heart attack or stroke
- Indispensable and inexpensive recipes
- Two common mutations, the key to ovarian cancer
| Keys to predict and prevent childhood atopic dermatitis Posted: 30 Jan 2012 07:40 AM PST Paint the walls, change the furniture and generally, making changes at home during pregnancy may increase the risk of atopic dermatitis baby develop infant, according to an observational study. In order to predict and prevent this disease, a group of researchers has analyzed the factors that most influence the manifestation of this pathology. They are not the only triggers the computer department of Medicine, National Taiwan University has found. “We found that the fungi that produce the humidity of the walls are also significantly associated with this type of dermatitis. “ According to Manuel Fernandez Lorent, Dermatology Group specialists Pedro Jaen (Madrid), “we must keep in mind that this is an observational, not randomized, so the conclusions drawn, but are to be taken into account, do not serve to establish a cause-effect relationship . “ For his part, Eduardo Fonseca Capdevila, Head of Dermatology, University Hospital of A Coruna, insists that first, “is essential to have the genetics that predispose to this disease.” “If parents have asthma, allergic rhinitis or atopic dermatitis, the baby’s chances of developing this skin disease increase,” argue the authors of the study, published in ‘British Journal of Dermatology’ .In addition, sex of the baby influences. It is clear from the results, the prevalence is higher among small (8.1% vs 5.7% of girls). Regardless of this investigation, which it has been shown, argues Dr. Fonseca Capdevila, is that the higher living standards, increased incidence of atopic dermatitis is recorded. There are several theories about it, but the most accepted is that “a better quality of life, better hygiene and fewer infections. Given that the immune system is designed to deal with such infections, avoid contact with parasites can cause the immune system does not develop normally and allergic reactions and even autoimmune diseases. We must not forget that avoiding germs survive more children die of diarrhea or parasitosis. Higher risk profileDrawing the conclusions about the triggers that most influence the development of this disease, the researchers established a predictive model based on these elements. Thus, they concluded that the highest risk of childhood atopic dermatitis (70.1%) as children whose parents were also suffering from the disease and, coincidentally, during pregnancy the mother had coexisted two situations at home: damp and reforms. By contrast, cases with minimal risk was for the girls that were not given none of the above conditions. In total, we examined the cases of 20,687 babies. The researchers conducted interviews with parents to learn about heredity and environmental factors when children had six months of life. The baby’s time is what distinguishes this work from another topic. As reflected in the article, most studies have been conducted so far are aimed at children from age three. “However, in half the cases the symptoms begin in the first six months of life . It is therefore important to examine in detail the triggers during pregnancy and breastfeeding that stage, “say the authors. These data underscore the study’s authors, “allow us to identify infants who are at high risk and gives us the ability to apply preventive measures, always at the environmental level.” |
| Know your risk of heart attack or stroke Posted: 30 Jan 2012 02:37 AM PST Want to know if you have a heart attack over your life? According to a team of researchers from the U.S. if you are a man, has already reached 45, not smoking, not overweight and no hypertension or diabetes, then your risk is only 1.4%. However, with two or more risk factors at his back, the odds increase to 49.5%. So it takes a study just published by the journal ‘The New England Journal of Medicine . For the first time, ensure those responsible for the work, “we are assessing the risk of coronary heart disease in both white and black women and men throughout life.” So far, they continue, the work focused especially white male population and a forecast of 10 years. In total, Northwestern University researchers examined more than 250,000 people over a period of 50 years. At 45, 55, 65 and 75 years, participants underwent an evaluation of their cholesterol levels, blood pressure, diabetes and snuff consumption. The authors focused on these aspects, being the main risk factors for cardiovascular disease or stroke . They found that men who reach 45 without these risk factors had only a 1.4% suffer any of these conditions. However, it was enough to smoke and had higher cholesterol levels for the chance to ascend to 49.5% . In the case of women, to reach 45 in top form, may suffer a heart attack or stroke by 4.1%. With two or more risk factors, the chances increase to 30.7%. “We saw that women had a higher risk of stroke than men, but less heart attacks,” the authors say in the article. This is because, according to Jaime Masjuán Vallejo, coordinator of the Stroke Unit at the Hospital Ramon y Cajal in Madrid, that “ they live longer and strokes tend to occur more often after 65. “ However, he continues, “the heart affects younger people and men, because they have poorer control of risk factors, such as the snuff.” As explained by Dr. Masjuán Vallejo, the results of this study “underscore the importance of prevention” and reveal that the efficacy of drugs to control diabetes or hypertension are much less effective in preventing cardiovascular events that reach 45 without such factors. “ Since the work includes a large sample of participants, says the Spanish specialist, “ are very significant findings . “ Above all, taking into account the need now exists to work more on prevention. “Before, I see people under 50 years with a stroke was exceptional. Now, every week we have a case and this is because we have the highest burden of obesity, hypertension, diabetes and snuff. We do not realize that a little descotrolen levels are, for example cholesterol, before 50, the risk of heart attack or stroke increases significantly. “ Researchers recall, therefore, that lifestyle is key, particularly diet, exercise and smoking cessation, which is what most helps reduce the risk factors leading to coronary heart disease or stroke. “From the standpoint of prevention, we must do more emphasis on the idea of doing everything possible not to develop diabetes , hypertension, smoking or earn extra kilos, “said one of the authors, Jarett Berry. This will be the most effective way to keep your heart in shape throughout life |
| Indispensable and inexpensive recipes Posted: 29 Jan 2012 08:35 PM PST In addition to prescribing drugs to relieve ailments, physicians should recommend, in writing in detail, two more things to their patients. One would be what kind of exercise should be done regularly and what other digital sources of credibility and prestige to which it can approach to learn of his illness. Has just been published in Spanish medical journal ‘Clinical Medicine’ , the greatest impact in our country, a thorough review of the indications is exercise. Experts Girona Faculty of Medicine concluded, after tracking the best that has been published in recent years on the subject, that physical activity-both moderate and intense, prevents, when done regularly, premature mortality produce a very high number of severe medical conditions. And it does so significantly. You have to name some of the most common and important. Ischemic heart disease, stroke, hypertension, colon cancer and breast cancer, type 2 diabetes, metabolic syndrome, obesity, osteoporosis, sarcopenia, functional dependence, falls in the elderly, cognitive impairment, anxiety and depression . The list is impressive, as are the percentages of risk reduction is achieved when the muscles move seriously and regularly. The challenge now is to convince the citizenry, so used to the couch and the lift-that health is not a thing of pills if not proposed sweat shirt at least every other day, and forever. The other unfinished business of any health system who wants no break in the future is to increase health literacy level of society. More dangerous than high cholesterol, high blood pressure and perhaps inadequate levels of glucose is ignorance. Only an informed society can promote health and prevent, manage the beginnings of an acute illness or manage much of a chronic process, if the sufferer. That is why health professionals should advise patients what are the most reliable sources that exist to raise some level of knowledge in biomedicine. That over 50% of cases is low |
| Two common mutations, the key to ovarian cancer Posted: 29 Jan 2012 02:32 PM PST
From studies conducted to date is known that between 6% and 15% of women with this type of tumor have these mutations. “These are the factors most important known genetic risk so far,” said Kelly Bolton, principal author of the research, published this week in the journal ‘The Journal of the American Medical Association’ . Not yet known what other genes or mutations are involved in other women who have the disease. With respect to BRCA2, a recent study “as related to improved survival, however, the role of BRCA1 was not very clear.” Bolton and his team decided to review from 26 observational studies that analyzed the survival of women with ovarian cancer. After evaluating the cases of 1,213 affected (909 with mutations in BRCA1 and 304 BRCA2) and 2666 women carry these variations, the authors observed that the survival rate at five years was 36% in the latter group. Among women who had BRCA1 mutations, the percentage increased to 44% and those with variations in BRCA2 to 52%. “Even taking into account other factors such as age or stage of tumor, the prognosis was still better among those with these mutations,” notes the researcher. In an editorial accompanying this paper, David Spriggs, Memorial Sloan Kettering Cancer Center (New York, USA), says that this is most significant study conducted to date by the number of people involved (a total of 3879 ). Discussed various ethnic groups and multiple continents, showing an X-ray of the situation more real, “even though the limitations that the authors assume,” lack of information on clinical aspects (such as stage or histology) some patients. “ A view shared by Joaquin Montal, Head of Oncology at the Hospital La Fe de Valencia, who notes that “the molecular alterations are those that will determine the prognosis of the disease rather than clinical parameters.” Clinical Implications The survival advantage among carriers of BRCA1 and BRCA2 in comparison with the rest were “somewhat lower” when the affected family history of ovarian, breast or both. According to experts, there is evidence that women who carry alterations in the BRCA1 or BRCA2 are also more likely to have breast cancer. And we know that a woman with a first degree relative who has had this tumor has three to four times more likely to develop it. “Our findings have important clinical implications for the management of these patients, “the researchers emphasize. In addition to observing a better prognosis in carriers of BRCA1 and BRCA2, also confirmed that they will have better response to certain treatments, like chemotherapy with platinum. As the study authors emphasize, this may help customize treatment according to the molecular alterations that occur in each person. “Once again, we approach to choose the most beneficial therapy for each case,” said Montal. Late detection Since ovarian cancer is one of the most malignant tumors, such studies are greeted with great anticipation. Currently, this disease accounts for 4% of cancer deaths in women, mainly because it is diagnosed in 19% of cases while the tumor is located, at which time healing opportunities are superior to 90%. As argued by Dr. Montal, “we have no specific diagnostic tests and, because of its location , it is difficult to suspect (no palpable signs as with breast cancer) and detect the tumor at an early stage. “ With the new findings, the researchers add, promote the idea of diagnostic tests to see what people are most at risk in order to establish more intensive monitoring and early detection of abnormalities in their ovaries. Today, says the Spanish physician, “when a person has breast cancer or ovarian cancer examines whether or not they are carriers of mutations in BRCA1 and BRCA2 genes. If yes, then establishing a close watch on their descendants . These genetic studies are already done in several Spanish hospitals. “ Given the importance of BRCA1 and BRCA2 in ovarian cancer, responsible for the editorial accompanying the article stresses that any research on this disease must take into account the mutations of these genes |
Encouraging news for those affected by ovarian cancer. According to a group of specialists from the National Cancer Institute U.S., those who have alterations in the BRCA1 and BRCA2 have a better prognosis.| You are subscribed to email updates from Public Health Clinic To stop receiving these emails, you may unsubscribe now. | Email delivery powered by Google |
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A test of saliva instead of blood tests to detect the 
